Moc-L-Tert-Leucine CAS 162537-11-3 Purity ≥99.0% (HPLC) Atazanavir Intermediate Factory

Short Description:

Chemical Name: Moc-L-Tert-Leucine 

CAS: 162537-11-3

Appearance: White to Off-White Crystals

Purity: ≥99.0% (HPLC)

Intermediate of Atazanavir HIV-1 Protease Inhibitor

High Quality, Commercial Production

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401 

E-Mail: alvin@ruifuchem.com


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162537-11-3 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Moc-L-Tert-Leucine (CAS: 162537-11-3) with high quality, commercial production, intermediate of Atazanavir HIV-1 Protease Inhibitor. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Moc-L-Tert-Leucine and Atazanavir intermediates, Please contact: alvin@ruifuchem.com 

162537-11-3 - Chemical Properties:

Chemical Name Moc-L-Tert-Leucine
Synonyms Methoxycarbonyl-L-tert-Leucine; N-(Methoxycarbonyl)-tert-Leucine; Atazanavir Related Compound A
CAS Number 162537-11-3
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H15NO4
Molecular Weight 189.21
Melting Point 109℃
Density 1.126±0.06 g/cm3 
Boiling Point 320.9±25.0℃ at 760 mmHg
Solubility Soluble in Ethyl Acetate and Methanol
Shipping Condition Shipped Under Ambient Temperature
COA & MSDS Available
Place of Origin Shanghai, China
Brand Ruifu Chemical

162537-11-3 - Specifications:

Item Specifications Specifications
Appearance White to Off-White Crystals White Crystals
Identification Methods HPLC; IR  Conforms
Purity/Analysis Method ≥99.0% (HPLC)  99.5% (HPLC)
Moc-L-Tle-Tle-OH ≤0.30%  0.04%
L-Moc-Dimer ≤0.30%  N/D
L-Tle-OH ≤0.10%  <0.10%
Methoxycarbonyl-L-Valine ≤0.10%   <0.10%
N-Acetyl-L-tert-Leucine ≤0.05% N/D
Individual Unkown Impurity ≤0.30%  0.14%
Total Impurities ≤1.00%  ≤1.0%
Enantiomer Content  ≤0.10% (By Chiral HPLC)  N/D
Water Content  ≤0.50% (By K.F)  0.19%  
Loss on Drying ≤0.50%  0.24%
Residue on Ignition ≤0.20%  <0.20%
Heavy Metals ≤10ppm <10ppm
Usage Amino Acid; Intermediate of Atazanavir (CAS 198904-31-3)  

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

Advantages:

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FAQ:

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162537-11-3 - Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Moc-L-Tert-Leucine (CAS 162537-11-3) with high quality. Moc-L-Tert-Leucine is a kind of amino acid deriviative. It is a very useful intermediate for efficient synthesis of the HIV protease inhibitor Atazanavir (CAS 198904-31-3) as well as Atazanavir sulfate (CAS 229975-97-7).

Atazanavir is an antiretroviral agent that has been approvedby the FDA for use in combination with other anti-RTagents for the treatment of HIV infections. The drug is always used in combination with RT inhibitors. Atazanavir is an inhibitor of HIV-1 protease (EC50=2.6 nM). In isolated cells, it has additive to moderately synergistic antiviral effects when combined with other antiretroviral drugs. As a result, it is commonly used in vivo in combination therapy for HIV-1 infection.

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