1-Boc-Piperazine CAS 57260-71-6 Purity >99.5% (GC) Factory

Short Description:

Chemical Name: 1-Boc-Piperazine

Synonyms: N-Boc-Piperazine

CAS: 57260-71-6

Purity: >99.5% (GC)

Appearance: White to Off-White Solid

High Quality, Commercial Production

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

57260-71-6 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-Boc-Piperazine (CAS: 57260-71-6) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

57260-71-6 - Chemical Properties:

Chemical Name	1-Boc-Piperazine
Synonyms	N-Boc-Piperazine; 1-(tert-Butoxycarbonyl)piperazine; N-(tert-Butoxycarbonyl)piperazine; tert-Butyl 1-Piperazinecarboxylate; tert-Butyl Piperazine-1-Carboxylate
CAS Number	57260-71-6
Stock Status	In Stock, Production Capacity 50 Tons per Month
Molecular Formula	C9H18N2O2
Molecular Weight	186.26
Melting Point	35.0~42.0℃
Density	1.030±0.06 g/cm3
Sensitive	Hygroscopic. Air Sensitive, Heat Sensitive
Solubility	Soluble in Methanol and Water
COA & MSDS	Available
Origin of Product	China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

57260-71-6 - Specifications:

Item	Specifications	Results
Appearance	White to Off-White Solid	White Solid
1-Boc-Piperazine Purity	>99.5% (GC)	99.8%
Melting Point	35.0~42.0℃	40.0~42.0℃
Moisture Content (by K.F)	<0.50%	0.1%
Piperazine	<0.10%	0.02%
Other Single Impurity	<0.10%	<0.10%
Solvent Residue (CHCl3)	<0.50%	<0.20%
Total Impurities	<0.50%	0.20%
Infrared Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications

57260-71-6 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. It is sensitive to air. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.

57260-71-6 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

57260-71-6 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

57260-71-6 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs 3263
WGK Germany 3
FLUKA BRAND F CODES 3-10-34
HS Code 2934999099
Hazard Class IRRITANT

57260-71-6 - Application:

1-Boc-Piperazine (CAS: 57260-71-6) is an N-Boc protected piperazine, is used as an organic intermediate, pharmaceutical intermediate. 1-Boc-Piperazine is a useful reagent for the preparation of anticancer agents.
1-Boc-Piperazine undergoes Buchwald-Hartwig amination with various aryl halides to form corresponding amine derivatives. It can be used to synthesize monosubstituted piperazine intermediates of many bioactive molecules and piperazine containing drug substances, such as trazodone.
In modern chemical pharmaceuticals, 1-Boc-Piperazine plays a very important role, because it is an important basic chemical raw material for many antitussive drugs, anti-allergic drugs, antipsychotic drugs, antibacterial drugs, various pesticides, etc. Due to its wide range of uses, increasing demand, accounting for a high proportion of the cost of various drugs, so reducing the industrialization cost of 1-Boc-Piperazine has very important industrial value and economic value.

57260-71-6 - Synthesis Method:

Synthesis Method: At present, the method of synthesizing 1-Boc-Piperazine is mainly to use anhydrous piperazine drops and ditert-butyl dicarbonate to selectively react to protect the nitrogen on one end of piperazine, so that the amino group on the other end is removed. In this reaction method, both ends of piperazine will be connected with ditert-butyl dicarbonate, and a large amount of water must be used for purification. Wash.